Immunoglobulin G (IgG), Serum

Preferred Specimen(s) 1.0 mL Serum

Instruction Overnight fasting is preferred

Transport Container Plastic Screw cap vial

Transport Temperature

Ambient 7 days,
Refrigerated 14 days

Reject Criteria

Gross hemolysis,
lipemic

Methodology Nephelometry

Clinical Significance Patients with low concentrations of IgG may have a wide variety of respiratory illnesses including recurrent otitis media, sinusitis, pneumonia, chronic obstructive airway disease, bronchiectasis, and asthma. Measurement of IgG may be useful in monitoring patients being treated for IgG monoclonal gammopathies and during replacement with intravenous immunoglobulins.