Plasminogen Activator Inhibitor (PAI-1)

Preferred Specimen(s) 1 mL plasma collected in a 3.2% sodium citrate (light blue-top) tube

Transport Container Plastic screw-cap vial

Transport Temperature Frozen

Reject Criteria Received thawed

Methodology Immunoassay

Clinical Significance Increased activity is associated with increased risk of arterial thrombosis, such as with unexplained premature myocardial infarction. As an acute phase reactant, the activity is increased after an acute event. Studies suggest PAI-1 may be a prognostic marker in early stage breast cancer.