Scl-70

Preferred Specimen(s) 1.0 mL Serum

Transport Container Plastic Screw cap vial

Transport Temperature

Refrigerated 3 days,
-20oC Long term

Reject Criteria Grossly Hemolysed

Methodology ELISA

Clinical Significance Scleroderma may be localized or diffuse [Progressive Systemic Sclerosis (PSS)] that may involve skin, gastrointestinal tracts, lungs, vascular and cardiac systems, and kidneys. Scl-70 Antibody is present in approximately 40% of patients with PSS.