Thrombophila Panel

Thrombophila Panel

Includes Protein-C Functional, Protein-S Functional, APC-R, Antithrombin III, ANA ELISA, Anti DsDNA,

Factor V Leiden, Complement C3, Complement C4, Lupus Anti Coagulant (screening), Anti Cardiolipin – IgG & Anti Cardiolipin IgM

Preferred Specimen(s) For Specimen requirements see individual Tests listed under Test Components.

Transport Container Plastic screw cap vial

Transport Temperature See individual tests for transport temperature

Reject Criteria

• Hemolyzed,
• lipemic,
• leaked &
• QNS specimens

Methodology

• Chromogenic; Enzyme Immunoassay Invader Assay/Signal Amplification Clotting Assay
• Fluorescence polarizaton Immunoassay Clot Detection

Clinical Significance Decreased antithrombin III activity, protein C activity, free protein S, and the presence of a factor V (Leiden) and/or factor II 20210G>A mutation each contribute to an increased risk of hereditary thrombophilia. Approximately 10% of factor V (Leiden) heterozygotes also carry the prothrombin 20210G>A mutation. Likewise, protein C and/or S deficiency have been reported with factor V (Leiden) mutation. Since venous thrombosis is a multifactorial disorder, presence of a second risk factor further increases the thrombotic risk.

Book Your test Now