CALCIUM, Random Urine

CALCIUM, Random Urine

Preferred Specimen(s):  10 mL random Urine. Collect urine with 25 mL 6N HCL

Transport Container: Sterile urine container or Plastic screw urine vial Transport

Temperature

• Refrigerated preferred;
• Room temperature acceptable;
• Frozen acceptable

Reject Criteria: None

Methodology: Spectrophotometry

Clinical Significance: Urinary calcium reflects dietary intake, rate of calcium absorption by the intestine and bone resorption. Urinary calcium is used primarily to evaluate parathyroid function and the effects of Vitamin D. A significant number of patients with primary hyperparathyroidism will have elevated urinary calcium. However, there are other clinical entities that may be associated with increased urine calcium: Sarcoidosis, Paget’s disease of bone, Vitamin D intoxication, hyperthyroidism and glucocorticoid excess. Decreased urine calcium is seen with thiazide diuretics, vitamin D deficiency and familial hypocalciuric hypercalcemia.

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