Anti Thyroid proxidase (Anti-TPO)

Anti Thyroid proxidase (Anti-TPO)

Preferred Specimen(s) 1.0 mL Serum

Transport Container Plastic screw cap vial

Transport Temperature Refrigerated 2 days

Reject Criteria Grossly hemolyzed specimen

Methodology Chemiluminescence

Clinical Significance Thyroid peroxidase (TPO) is an enzyme that catalyzes the iodination and coupling steps in thyroid hormone biosynthesis. It is now known to be the principal microsomal antigen against which antibodies are directed in autoimmune thyroid diseases. The main use of this test is to confirm that a patient diffuse goiter and/or hypothyroidism is due to autoimmune thyroiditis. The test may also help distinguish Graves’s disease from toxic nodular goiter. The TPO antibody measurement has replaced the thyroid antimicrosomal antibody (AMA) measurement. TPO antibodies may be detected in individuals without clinically significant thyroid disease. They do not define the patient’s thyroid functional status.

Book Your test Now