Hepatitis Be Antigen and Antibodies serum

Hepatitis Be Antigen and Antibodies serum

Preferred Specimen(s) 1 mL serum

Transport Container Plastic screw-cap vial

Transport Temperature

• Refrigerated 5 days,
• -20oC 4 weeks

Reject Criteria

• Gross hemolysis
• Lipemia
• Plasma

Methodology Chemiluminescence

Clinical Significance Persistence of HBeAg for greater than 6 months is a prognostic indicator of a chronic hepatitis B virus carrier state. The presence of anti-HBe serves to distinguish these two periods and confirms a sero-conversion. The appearance of anti-HBe or the sero-conversion from HBeAg positivity to anti-HBe positivity thus indicates a reduced level of infectious virus because virus replication has decreased. Though resolution of the disease generally follows, an HBsAg carrier state may persist. Anti-HBe positivity in this carrier is often associated with chronic asymptomatic infection. During the HBeAg positive stage, therefore, Hepatitis B patients are at increased risk of transmitting the virus to their contacts. Persistence of HBeAg in the epatitis B virus carrier is often associated with chronic active hepatitis.

Book Your test Now