Saccharomyces (ASCA) IgA

Preferred Specimen(s) 1.0 mL Serum

Transport Container Plastic Screw cap vial

Transport Temperature Refrigerated, stable 48 hours

Reject Criteria Grossly Hemolysed

Methodology ELISA

Clinical Significance Antibodies to Saccharormyces cerevisiae are found in approximately 75% of patients with Crohn’s disease, 15% of patients with ulcerative colitis, and 5% of the healthy population. High titers of antibody increase the likelihood of disease, and specifically Crohn’s disease and are associated with more aggressive disease.