Toxoplasma Gondii Antibody (IgM)

Toxoplasma Gondii Antibody (IgM)

Preferred Specimen(s) 1 mL serum

Transport Container Plastic leak proof container

Transport Temperature Refrigerated 3 days

Reject Criteria

• Gross hemolysis
• Hyperlipemia

Methodology CLIA

Clinical Significance Toxoplasmosis is a parasitic infection of humans caused by the protozoan toxoplasma gondii. In acute infections in immuno-competent hosts, only 10-20% of toxoplasma infections is symptomatic and usually present as asymptomatic cervical lymphadenopathy. The clinical picture may resemble infectious mononucleosis or CMV infection and the course is self-limited. Acute toxoplasmosis in immunodeficient hosts is the most common cause of intracerebral mass lesions. Serologic tests rarely confirm the diagnosis of toxoplasmic encephalitis in AIDS patients. Although a negative test result for specific IgG antibody diminishes the likelihood of toxoplasmic encephalitis, approximately 3% of patients with toxoplasmic encephalitis do not have toxoplasma antibody in their serum.

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